Famous Lexingtonians
- Mary E. Britton, 1855-1925
- Claim to Fame: Lexington's first female physician, educator
- William Wells Brown, 1814-1884
- Claim to Fame: first African-American novelist and published playwrite in the U.S.
- Peter "Old Captain" Duerett, 1733-1823
- Claim to Fame:
- London Ferrill, 1789-1854
- Claim to Fame:
- William H. Fouse
- Claim to Fame:
- Mr. Fouse was a regionally recognized educator and the first principal of Paul Laurence Dunbar High School. He served as principal of this important community institution from 1922-1938.
- Isaac Scott Hathaway, 1872-1967
- Claim to Fame: sculptor
- James "Sweet Evening Breeze" Herndon
- Claim to Fame:
- "Sweets" was a much beloved local person who was gender-bending long before David Bowie or Ru Paul.
- John E. Hunter, -1956
- Claim to Fame: Physician, President of the National Medical Association
- Eliza Belle Jackson, 1848-1942
- Claim to Fame: Educator
- Isaac Lewis
- Claim to Fame: Jockey, KY Derby winner on Montrose (1887)
- Bourbon County native
- Garrett A. Morgan, 1877-1963
- Claim to Fame: inventor of the traffic light and gas mask
- Born in Paris, KY.
- Isaac Burns "Ike" Murphy, 1861-1896
- Claim to Fame: Most winning jockey in thoroughbred racing history
- James "Soup" Perkins
- Claim to Fame: Jockey, KY Derby winner on Halma (1895)
- William Walker
- Claim to Fame: Jockey, KY Derby winner on Baden-Baden (1877), trainer and horse breeder
- Born in Versailles.
- T. T. Wendell
- Claim to Fame: Physician